ea0059p052 | Bone and calcium | SFEBES2018
Stevenson Mark
, Pagnamenta Alistair T
, Mack Heather G
, Savige Judith A
, Lines Kate E
, Taylor Jenny C
, McCredie David A
, Thakker Rajesh V
Bartters syndrome (BS) and Gitelmans syndrome (GS) are renal tubular disorders affecting reabsorption of sodium, potassium and chloride. Common clinical features include muscle cramps and weakness, hypokalaemia, hypochloraemic metabolic alkalosis and elevated plasma aldosterone concentrations. Urinary calcium excretion and plasma magnesium concentrations may be differentiating features, such that hypomagnesaemia and hypocalciuria are typical of GS, and hypercalciur...